What Is Ibrance (Palbociclib)?
Ibrance, also known by its generic name Palbociclib, is an oral medication prescribed for the treatment of certain types of breast cancer. It is specifically used for patients with HR-positive, HER2-negative breast cancer, and is often prescribed in combination with other medications, such as letrozole, to help slow the progression of the disease. Ibrance works by inhibiting specific enzymes in cancer cells that are responsible for cell division, effectively stopping or slowing the growth of cancerous cells in the body. This targeted therapy is an important part of the treatment plan for individuals with advanced or metastatic breast cancer, offering a potentially effective way to manage the disease.
How Does Ibrance (Palbociclib) Work?
Ibrance works by targeting and inhibiting cyclin-dependent kinases (CDKs) 4 and 6, enzymes that play a key role in regulating the cell cycle, which controls how cells divide and grow. By blocking these enzymes, Ibrance prevents cancer cells from dividing, thereby slowing down or stopping the growth of tumors. This helps to limit the spread of cancer within the body, especially in HR-positive, HER2-negative breast cancer, where these pathways are often overactive. When combined with hormonal therapies such as letrozole, Ibrance can provide an enhanced effect, further inhibiting the growth of cancer cells and improving the overall outcome for patients.
Benefits of Using Ibrance (Palbociclib)
Targeted Therapy
Ibrance offers a targeted approach to cancer treatment by focusing specifically on the CDK 4/6 pathway, which is crucial in the growth and proliferation of certain cancer cells. This allows for a more focused treatment, potentially reducing the impact on healthy cells and minimizing some of the side effects associated with traditional chemotherapy.
Effective in Combination Therapy
When used in combination with other treatments, such as letrozole, Ibrance has been shown to significantly improve outcomes for individuals with HR-positive, HER2-negative breast cancer. The combination of hormonal therapy and CDK 4/6 inhibition can help slow disease progression, allowing patients to better manage their condition.
Convenient Oral Medication
Ibrance is available in an easy-to-take oral tablet form, which can be taken at home, making it a convenient option for many patients. This oral administration eliminates the need for frequent trips to the hospital or clinic for injections or infusions, allowing individuals to maintain a better quality of life during their treatment.
Improved Progression-Free Survival
Clinical studies have shown that Ibrance, when combined with hormonal therapies, significantly improves progression-free survival in patients with HR-positive, HER2-negative advanced breast cancer. This means that the disease is less likely to worsen or spread while the patient is on treatment, providing an important benefit in managing the disease.
Uses of Ibrance (Palbociclib)
Ibrance is primarily used to treat HR-positive, HER2-negative breast cancer, especially in patients with advanced or metastatic stages of the disease. It is commonly prescribed in combination with hormonal therapies, such as letrozole, to slow the progression of the cancer and manage symptoms more effectively. Ibrance is typically used in patients who have not yet received prior chemotherapy for metastatic disease or those who are experiencing a recurrence of the disease.
Dosage Forms and Strengths
Ibrance is available in the following dosage forms:
- Ibrance 125 mg Tablets (Palbociclib 125 mg)
- Ibrance 100 mg Tablets (Palbociclib 100 mg)
- Ibrance 75 mg Tablets (Palbociclib 75 mg)
The specific dosage prescribed will depend on your medical condition, overall health, and how your body responds to the medication. Your healthcare provider will determine the appropriate dose based on these factors.
How to Use Ibrance (Palbociclib)
Ibrance is typically taken once a day, with or without food. It is important to take the medication exactly as prescribed by your healthcare provider, swallowing the tablets whole with a glass of water. Do not chew, break, or crush the tablets, as this may affect the medication’s effectiveness.
Ibrance (Palbociclib) Missed Dose
If you miss a dose of Ibrance, take it as soon as you remember, unless it is almost time for your next scheduled dose. In this case, skip the missed dose and take your next dose as directed. Never take two doses at once to make up for a missed dose, and always consult your healthcare provider if you have any concerns about missed doses.
Ibrance (Palbociclib) Storage Instructions
Ibrance should be stored at room temperature, between 68°F and 77°F (20°C and 25°C), away from heat and moisture. Keep the medication in its original container, tightly closed, and out of reach of children. Do not store Ibrance in the bathroom or near a sink, as excessive moisture can affect the integrity of the medication.
Ibrance (Palbociclib) Side Effects
Common Side Effects:
- Nausea
- Fatigue or weakness
- Decreased appetite
- Hair loss or thinning
- Diarrhea
- Mouth sores
Serious Side Effects:
- Low white blood cell count (which may increase the risk of infection)
- Severe allergic reactions (rash, difficulty breathing, swelling of the face or throat)
- Severe liver problems (yellowing of the skin or eyes, dark urine)
- Breathing difficulties or persistent cough
If you experience any serious side effects, contact your healthcare provider immediately for guidance on managing the symptoms.
Ibrance (Palbociclib) Overdose
Overdosing on Ibrance may result in severe side effects, including a significant decrease in blood cell counts, making you more susceptible to infections. If you suspect an overdose, seek medical attention immediately. Your healthcare provider will assess the situation and provide the necessary treatment.
Where to Buy Ibrance (Palbociclib)
You can conveniently buy Ibrance (Palbociclib) online through 365 Script Care. We offer fast, secure, and reliable shipping to ensure that your medication reaches you in a timely and efficient manner. With competitive pricing and top-notch customer service, we make it easier for you to access Ibrance and continue your treatment without delay.
Place your order today and begin your journey towards better managing your condition with Ibrance, delivered directly to your door by 365 Script Care. Let us help you stay on track with your treatment plan and achieve the best possible outcomes.
Contact Information
For comprehensive support and inquiries regarding your medication order or any other questions, please contact us via our toll-free number at 1-888-821-0245. You can also send a fax to 1-888-338-6690 or email us at info@365scriptcare.com. Our dedicated team is available Monday through Friday from 10:00 am to 8:00 pm CST, and on weekends from 9:00 am to 5:00 pm CST, ensuring that we are here for you every day of the year.
For swift assistance, we encourage you to contact our customer support during business hours so you can interact directly with our team for immediate help with orders, shipping inquiries, or product information.
All orders for medications sourced from Canada take 10-14 business days to receive from the date shipped. For all internationally sourced medications, it may take 15-20 business days to receive from the date shipped. For any issues regarding your tracking or receiving your order, please contact the toll-free 1-800 number to request to speak to a member of the loyalty team.
FAQs
Ibrance is specifically indicated for hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced breast cancer. Your doctor will determine if Ibrance is suitable for your particular stage and type of breast cancer.
Before starting Ibrance treatment, inform your doctor about all medications you are currently taking, including prescription drugs, over-the-counter medications, and supplements. Some medications may interact with Ibrance, so it’s crucial to discuss potential interactions with your healthcare provider.
The duration of Ibrance treatment will depend on your individual response and your doctor’s recommendation. Typically, treatment with Ibrance is continued as long as it remains effective and well-tolerated. Your doctor will monitor your progress and adjust your treatment plan as needed.