Abacavir Sulfate / Lamivudine

**Adults and children weighing at least 25 kg:** Take one tablet orally once daily in combination with other antiretroviral agents, with or without food[5]. **Children weighing less than 25 kg:** This fixed-dose combination should not be used; individual components should be prescribed instead, as dose adjustments cannot be achieved with this product[7]. **Patients with renal or hepatic impairment:** The medication is not recommended for patients with creatinine clearance less than 30 mL/min; individual components should be used instead[2]. The medication can be administered as a single daily dose or in divided doses (e.g., 300 mg abacavir and 150 mg lamivudine twice daily)[9]. For pediatric patients taking the tablet form, ability to swallow tablets must be assessed before prescribing[5].