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Dexilant, produced by Takeda Pharmaceuticals, is a branded medication categorized as a proton pump inhibitor (PPI). It is prescribed for the treatment of erosive esophagitis (EE), relief from heartburn, and management of GERD in adults and individuals aged 12 and above. Despite generally being well-tolerated, individuals must be aware of potential side effects associated with Dexilant use. Common side effects include stomach pain and diarrhea, while less frequent but more severe side effects may involve serious allergic reactions.

Explore further information on Dexilant’s side effects and discover preventive measures.

What is Dexilant?

Dexilant, with the generic name dexlansoprazole, is a medication belonging to the class of proton pump inhibitors (PPIs). Manufactured by Takeda Pharmaceuticals, it is commonly prescribed to address various gastrointestinal conditions. Dexilant is utilized for the healing of erosive esophagitis (EE), providing relief from heartburn, and treating gastroesophageal reflux disease (GERD) in both adults and children aged 12 and older.

As a PPI, Dexilant works by reducing the production of stomach acid, which is beneficial in alleviating symptoms associated with conditions like GERD. While generally well-tolerated, it is important for individuals using Dexilant to be aware of potential side effects, with common ones including stomach pain and diarrhea. Additionally, though less frequent, more serious side effects such as serious allergic reactions can occur.

Benefits of Dexilant

Dexilant (dexlansoprazole) offers several benefits in managing gastrointestinal conditions, particularly those related to excess stomach acid. Some key benefits of Dexilant include:

  • Treatment of GERD (Gastroesophageal Reflux Disease): Dexilant is effective in treating GERD, a condition where stomach acid frequently flows back into the esophagus, causing symptoms like heartburn and acid regurgitation.
  • Healing of Erosive Esophagitis (EE): Dexilant aids in the healing of erosive esophagitis, a condition characterized by inflammation and damage to the lining of the esophagus due to stomach acid.
  • Relief from Heartburn: One of the primary benefits of Dexilant is its ability to provide relief from heartburn, a common symptom of GERD. By reducing stomach acid production, it helps alleviate the burning sensation associated with heartburn.
  • Proton Pump Inhibition: As a proton pump inhibitor (PPI), Dexilant works by inhibiting the proton pump in the stomach lining, thereby reducing the secretion of gastric acid. This mechanism helps in preventing the recurrence of acid-related symptoms.
  • Long-Lasting Acid Control: Dexilant is known for its extended-release formulation, providing longer-lasting acid control compared to some other medications in the same class.

It’s important to note that while Dexilant offers these benefits, its use should be supervised by a healthcare professional. Additionally, individuals should be aware of potential side effects and follow their healthcare provider’s recommendations for optimal results. Always consult with a healthcare professional for personalized advice based on individual health conditions.

Side Effects of Dexilant

While Dexilant (dexlansoprazole) is generally well-tolerated, like any medication, it may be associated with certain side effects. It is important for individuals using Dexilant to be aware of potential adverse reactions and promptly inform their healthcare provider if they experience any concerning symptoms. Common side effects of Dexilant may include:

  • Stomach Pain: Some individuals may experience abdominal discomfort or stomach pain as a side effect of Dexilant.
  • Diarrhea: Dexilant use may be associated with diarrhea in some cases.

Less frequently, but more serious side effects may occur. It is crucial to seek immediate medical attention if any of the following severe reactions are observed:

  • Serious Allergic Reactions: While rare, serious allergic reactions to Dexilant can occur. Symptoms may include rash, itching, swelling, severe dizziness, or difficulty breathing. If any of these signs are present, emergency medical assistance is essential.

It’s important to note that this list is not exhaustive, and individuals should consult their healthcare provider for a comprehensive understanding of potential side effects associated with Dexilant. Additionally, healthcare professionals may guide how to manage or mitigate these side effects for optimal treatment outcomes.


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Long-term Side Effects of Dexilant

Prolonged use of Dexilant, particularly beyond the recommended duration, may pose certain risks. Individuals must be aware of potential long-term side effects and discuss them with their healthcare provider.

Possible long-term considerations related to Dexilant use may include:

  • Risk of Bone Fractures: Some studies suggest that extended use of proton pump inhibitors (PPIs), the class of medications to which Dexilant belongs, may be associated with a slightly increased risk of bone fractures, especially in the hip, wrist, and spine.
  • Potential for Kidney Issues: There have been reports of an association between long-term PPI use and potential kidney-related concerns, including chronic kidney disease. However, more research is needed to establish a definitive link.
  • Risk of Infections: Prolonged use of PPIs may slightly elevate the risk of certain infections, particularly in the gastrointestinal tract.

It’s important to note that the decision to use Dexilant for an extended period should be made in consultation with a healthcare professional, considering the individual’s specific health condition and the potential benefits versus risks.

Does Dexilant Cause Weight Gain as a Side Effect?

Is weight gain a potential side effect of Dexilant? While Dexilant (dexlansoprazole) is primarily used to manage gastroesophageal reflux disease (GERD) and related conditions, weight gain is not commonly reported as a side effect. Most reported side effects are mild and transient, such as stomach pain or diarrhea. 

However, individual responses can vary, and any concerns about side effects should be discussed with a healthcare professional overseeing the Dexilant treatment. Monitoring weight and overall health is crucial during medication use, and any unexpected changes should be promptly addressed with a healthcare provider for appropriate guidance.

What Happens When You Discontinue the Use of Dexilant?

Discontinuing the use of Dexilant, a proton pump inhibitor used to treat conditions like gastroesophageal reflux disease (GERD), requires careful consideration. Abrupt cessation may lead to a resurgence of acid-related symptoms, such as heartburn and acid reflux, as Dexilant plays a crucial role in reducing stomach acid production. Gradual tapering, under the guidance of a healthcare professional, is often recommended to manage the transition and minimize the likelihood of symptom recurrence.

It’s essential to communicate with your healthcare provider before discontinuing Dexilant, as they can provide personalized advice based on your health status. They may recommend alternative treatments, lifestyle modifications, or further evaluations to ensure a smooth transition while effectively managing your gastrointestinal health.

How to Prevent Dexilant Side Effects

Minimizing the risk of Dexilant (dexlansoprazole) side effects involves adopting certain preventive measures. Follow these guidelines to help prevent potential adverse reactions:

  • Take as Prescribed: Adhere to your healthcare provider’s prescribed dosage and administration instructions. Avoid altering the dosage or frequency without consulting your healthcare professional.
  • Regular Monitoring: Keep regular follow-up appointments with your healthcare provider to monitor your response to Dexilant. This allows for timely adjustments to the treatment plan if needed.
  • Discuss Medical History: Inform your healthcare provider about your medical history, including any pre-existing conditions or allergies. This information enables them to make informed decisions about the suitability of Dexilant for your specific health circumstances.
  • Be Mindful of Interactions: Communicate any other medications, supplements, or herbal remedies you are taking to your healthcare provider. Certain substances may interact with Dexilant, potentially affecting its effectiveness or increasing the risk of side effects.
  • Lifestyle Modifications: Implement lifestyle changes, such as maintaining a healthy diet, avoiding excessive alcohol consumption, and refraining from smoking, as these factors can contribute to the effectiveness of Dexilant and reduce the likelihood of side effects.

Always consult your healthcare provider before starting or stopping any medication and promptly report any unusual symptoms or concerns during Dexilant use. Individual responses to medications can vary, and personalized medical advice is crucial to ensuring a safe and effective treatment experience.

When is the Best Time to Take Dexilant?

The optimal time to take Dexilant (dexlansoprazole) is typically in the morning, before a meal. It is recommended to take Dexilant at least 30 minutes before eating, as this allows the medication to be most effective in suppressing stomach acid production when food is subsequently consumed. This timing enhances its ability to manage conditions such as gastroesophageal reflux disease (GERD).

However, it’s important to follow the specific instructions provided by your healthcare provider or the medication label. Individual circumstances may vary, and your healthcare professional will offer personalized guidance based on your health condition and treatment plan.

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In conclusion, while Dexilant (dexlansoprazole) is generally well-tolerated and provides effective relief for gastroesophageal reflux disease (GERD) and related conditions, it’s crucial to be aware of potential side effects. Common side effects, such as stomach pain and diarrhea, are usually mild and transient. However, individuals should promptly report any unusual or severe reactions to their healthcare provider. 

Understanding and monitoring potential side effects, along with maintaining open communication with a healthcare professional, ensures a balanced approach to managing GERD symptoms while minimizing any associated risks.

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