Apixaban – Usage, Side Effects, Dosage, Cost

Anticoagulant drugs are crucial in the prevention of blood clots and lowering the chances of stroke or deep vein thrombosis. Apixaban stands out as a medication known for its effectiveness and safety. This article explores the realm of Apixaban, offering insights into its applications, advantages, potential side effects, and more.

What Is Apixaban?

Apixaban is an oral anticoagulant that belongs to a class of medications known as direct oral anticoagulants (DOACs). 

It is commonly marketed under the brand name Eliquis. Apixaban is primarily prescribed to reduce the risk of stroke and systemic embolism in individuals with atrial fibrillation, a condition characterized by irregular heartbeats.

How Does Apixaban Work?

Apixaban works by inhibiting a crucial blood clotting factor called Factor Xa. By doing so, it prevents the formation of blood clots, which can lead to serious medical conditions, including strokes and pulmonary embolisms. Unlike traditional anticoagulants, such as warfarin, Apixaban does not require frequent blood monitoring.

Uses of Apixaban

Apixaban is used for several medical purposes, primarily related to its anticoagulant (blood-thinning) properties. Here are the primary uses of Apixaban:

• Prevention of Stroke and Systemic Embolism in Atrial Fibrillation: Apixaban is commonly prescribed to individuals with non-valvular atrial fibrillation, a heart rhythm disorder. It helps reduce the risk of stroke and systemic embolism by preventing the formation of blood clots in the heart that can travel to the brain or other parts of the body.

• Treatment and Prevention of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE): Apixaban is used to treat and prevent DVT, which involves the formation of blood clots in the deep veins, typically in the legs. It is also employed for the prevention of PE, a condition where these clots travel to the lungs and can be life-threatening.

• Reducing the Risk of Recurrent Blood Clots: Apixaban is prescribed to individuals who have experienced DVT or PE to reduce the risk of recurrent blood clots.

• Prophylaxis After Orthopedic Surgery: In some cases, Apixaban may be used as prophylaxis (preventative treatment) to reduce the risk of blood clots in patients undergoing certain orthopedic surgeries, such as hip or knee replacement.

Side Effects of Apixaban

While Apixaban is generally well-tolerated, it may cause some side effects, including:

• Easy bruising
• Nosebleeds
• Gastrointestinal discomfort
• Headache

Apixaban Brand Name

The brand name for Apixaban is Eliquis. 

Eliquis is a widely recognized and prescribed medication used as an oral anticoagulant to reduce the risk of stroke and systemic embolism in patients with atrial fibrillation, as well as for the treatment of deep vein thrombosis and pulmonary embolism.

It is known for its convenience, effectiveness, and lower risk of major bleeding compared to some other anticoagulants.

Apixaban Drug Class

Apixaban belongs to the class of medications known as direct oral anticoagulants (DOACs). As an anticoagulant, its primary mechanism of action is to inhibit Factor Xa, a crucial component in the blood clotting cascade. This class of drugs is used to prevent the formation of blood clots, reducing the risk of conditions such as stroke, deep vein thrombosis (DVT), and pulmonary embolism. Unlike traditional anticoagulants like warfarin, DOACs like Apixaban offer the advantage of simplified dosing and do not require frequent blood monitoring, making them a more convenient option for patients in need of anticoagulant therapy.

Apixaban Dosing

The dosing of Apixaban can vary depending on the medical condition it is prescribed for. However, for most common indications:

• Atrial Fibrillation: The standard dose for reducing the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation is typically 5 milligrams (mg) taken orally twice daily. In some cases, a lower dose of 2.5 mg twice daily may be recommended based on specific patient factors such as age, weight, and kidney function.
• Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE) Treatment: The initial dose for the treatment of DVT or PE is usually 10 mg taken orally twice daily for the first 7 days, followed by 5 mg taken orally twice daily.

It’s important to note that individual dosing may vary, and patients should always follow their healthcare provider’s instructions regarding the correct dosage and administration of Apixaban. Additionally, any adjustments or changes to the dosing regimen should be made under the guidance of a medical professional.

Apixaban Classification

Apixaban is classified as a direct oral anticoagulant (DOAC), also known as a non-vitamin K antagonist oral anticoagulant (NOAC). It falls under the broader category of anticoagulant medications, which are substances that prevent the formation of blood clots or inhibit their growth. 

Apixaban specifically works by targeting Factor Xa in the blood clotting cascade, thereby reducing the risk of thromboembolic events, such as stroke and deep vein thrombosis. This classification distinguishes Apixaban from traditional anticoagulants like warfarin, which operate through a different mechanism and require regular monitoring.

Foods to Avoid with Apixaban

When taking Apixaban or any anticoagulant medication, it’s essential to be mindful of your diet to avoid potential interactions or complications. Here are some foods and dietary considerations to keep in mind:

1. Vitamin K-Rich Foods: Vitamin K plays a role in blood clotting, so it’s important to maintain a consistent intake of foods rich in vitamin K to avoid fluctuations in their levels. While you don’t need to completely avoid vitamin K-rich foods, it’s advisable to consume them in moderation. Examples of such foods include spinach, kale, broccoli, and Brussels sprouts.
2. Grapefruit and Grapefruit Juice: Grapefruit and grapefruit juice can interact with Apixaban and affect its metabolism, potentially increasing its blood-thinning effects. It’s best to avoid or limit consumption of these products while taking Apixaban.
3. Alcohol: Excessive alcohol consumption can increase the risk of bleeding, which is a concern when taking anticoagulants like Apixaban. It’s advisable to drink alcohol in moderation and consult your healthcare provider for specific guidance based on your individual health.
4. Cranberry Products: While the interaction between cranberry products (e.g., cranberry juice) and Apixaban is not fully understood, it’s prudent to consume them in moderation. Some studies suggest that large amounts of cranberry products might increase the risk of bleeding.
5. Supplements: Be cautious with dietary supplements, especially those containing vitamin K, garlic, ginger, ginseng, or ginkgo biloba. These supplements may have blood-thinning properties or interact with Apixaban. Consult your healthcare provider before taking any new supplements.
6. Maintain a Consistent Diet: Consistency in your dietary habits can help maintain stable levels of vitamin K and minimize potential interactions. If you plan to make significant changes to your diet, discuss them with your healthcare provider.
7. Green Tea: Green tea contains vitamin K and may have mild anticoagulant properties. While moderate consumption is generally considered safe, avoid excessive consumption, especially if you are taking Apixaban.

Always follow your healthcare provider’s advice regarding dietary restrictions and considerations while taking Apixaban or any anticoagulant. They can provide personalized guidance based on your specific medical condition and medication regimen.

Overall, Apixaban is a highly effective anticoagulant medication used to prevent strokes, treat deep vein thrombosis and pulmonary embolism, and reduce the risk of major bleeding. Its convenience, reduced side effects, and overall efficacy make it a popular choice among healthcare providers and patients alike.

Apixaban Cost

The price of Apixaban can fluctuate depending on factors such as location, prescribed dosage, insurance coverage, and whether it’s a brand-name or generic version. Brand-name Apixaban, such as Eliquis, is generally more expensive. Insurance coverage can significantly affect out-of-pocket expenses, and generic alternatives may offer a more budget-friendly option. Additionally, patient assistance programs and discounts might be available to help with affordability. For the most current pricing and assistance options, it’s advisable to consult with your healthcare provider or pharmacist.

How to Buy Apixaban in the USA Online for Affordable Price

To buy Apixaban online in the USA at reasonable prices, start by consulting your healthcare provider for a prescription and insurance verification. Then, find reputable online pharmacies in the USA that require a valid Apixaban prescription. Compare prices, explore generic options, and look for discounts or assistance programs. Be mindful of shipping fees, and return policies, and prioritize privacy and security when choosing an online pharmacy. Additionally, seek advice from your local pharmacist for proper medication use and peace of mind, ensuring a budget-conscious and secure Apixaban purchase.

Order Apixaban Online at 365 Script Care

Ordering Apixaban online at 365 Script Care is a convenient and accessible option for obtaining your medication. To initiate the process, you can visit the 365 Script Care website and follow their ordering instructions. Make sure you have a valid prescription from your healthcare provider, as this is typically required for purchasing prescription medications online. Additionally, check for any available discounts or promotions that might help you save on the cost of Apixaban. Ensure that you provide accurate shipping information and review the delivery times. It’s essential to prioritize safety and privacy when ordering medication online, so choose reputable and licensed online pharmacies like 365 Script Care to ensure you receive genuine and effective Apixaban.